Maloff Protect 250mg/100mg Tablets

Active Ingredients: Each film-coated tablet contains 250mg Atovaquone and 100mg Proguanil Hydrochloride.

Other Ingredients: Poloxamer 188, microcrystalline cellulose, povidone K30, sodium starch glycolate, magnesium stearate, hypromellose, titanium dioxide (E171), iron oxide red (E172), and macrogols.

Maloff Protect belongs to a group of medicines called antimalarials. It is specifically indicated for the chemoprophylaxis of Plasmodium falciparum malaria in adults. Because it contains a combination of atovaquone and proguanil, it is effective even in areas where the malaria parasite may be resistant to other types of antimalarial drugs.

• Store at room temperature
• Do not use after the expiry date.
• KEEP OUT OF THE SIGHT AND REACH OF CHILDREN

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• Bite Prevention: No antimalarial is 100% effective. You must also use bite avoidance measures such as insect repellents, wearing long sleeves/trousers, and sleeping under mosquito nets.
• Travel Advice: Always check the latest travel health advice for your specific destination, as malaria risk and resistance patterns can change.
• Interactions: Tell your pharmacist if you are taking other medicines, particularly warfarin (blood thinner), metoclopramide (for nausea), or certain antibiotics like tetracycline or rifampicin.

Like all medicines, Maloff Protect can cause side effects, although not everyone gets them. Most side effects are mild and disappear once the medication is stopped.

• Very Common: Headache, feeling sick (nausea), being sick (vomiting), stomach pain, and diarrhoea.
• Common: Dizziness, sleeping problems (insomnia), strange dreams, depression, loss of appetite, fever, rash, and cough.
• Serious (Seek medical help immediately): Severe allergic reactions such as sudden wheezing, tightness in the chest, swelling of the eyelids or face, or a widespread itchy rash.

Maloff Protect is suitable for adults aged 18 years.

Do not take Maloff Protect if you:

• Are allergic to atovaquone, proguanil hydrochloride, or any of the other ingredients.
• Have severe kidney disease or liver disease.
• Are pregnant or breastfeeding (unless specifically prescribed by a doctor).
• Have a history of epilepsy, convulsions, or depression.

For the best protection, it is vital to take the full course of tablets exactly as directed:

• Starting the course: Take one tablet daily for 1 to 2 days before entering a malaria-endemic area.
• During your stay: Take one tablet daily at the same time each day while you are in the area.
• After leaving: Continue taking one tablet daily for a further 7 days after returning to a malaria-free area.

Tablets should be swallowed whole with food or a milky drink to ensure maximum absorption. If you vomit within one hour of taking a dose, you must take another tablet immediately.

Malaria is spread by the bite of an infected mosquito, which passes the malaria parasite into the bloodstream. Maloff Protect prevents the infection from developing by targeting the parasite at different stages of its life cycle. Atovaquone disrupts the parasite’s energy production, while proguanil stops the parasite from multiplying within red blood cells. Together, they provide high-level protection against the most dangerous form of malaria.