Nevolat Injections

Nevolat is a once daily weight loss injection, injected under the skin, usually into the stomach, upper thigh or upper arm. It can be taken at any time of day, with or without food though it should be injected around the same time each day. The injection sites should be rotated to reduce the risk of injection site reactions.

Nevolat comes in a pre-filled pen designed for easy self-injection. To use, follow the below steps:

1. Wash your hands thoroughly

2. Remove the outer cap and attach a new needle to the pen

3. Check the solution - it should be clear and colourless. Do not use if cloudy or contains particles

4. Select your injection site and gently clean with an alcohol wipe

5. Prepare the Nevolat pen by rotating the dose counter to the correct dose

6. Remove the inner needle cap

7. Inject under the skin at a 90-degree angle

8. Hold the Nevolat pen in place for a few seconds to ensure the full dose has been delivered

9. Safely remove the used needle and dispose in a sharps container

10. Replace the cap and store appropriately

The dose counter shows each individual dose that can be injected, 0.6mg, 1.2mg, 1.8mg, 2.4mg and 3mg, making it easier to inject.

Nevolat weight loss treatment starts at a low dose which is gradually increased over the first five weeks of treatment. Using the treatment in this way, reduces the risk of gastric side effects, allowing the body to gradually adjust to the treatment.

• Week 1 - 0.6mg once daily

• Week 2 - 1.2mg once daily

• Week 3 - 1.8mg once daily

• Week 4 - 2.4mg once daily

• Week 5 onwards - 3mg once daily. This is the maintenance dose which you would then remain on for the remaining duration of your treatment. Do not inject Nevolat at any dose higher than 3mg once daily.

In the case of a missed dose, if it is remembered within 12 hours from when you usually inject, use as soon as you remember. However, if more than 12 hours have passed since you should have used Nevolat, you should skip the dose missed and inject your next dose the following day at the usual time.

Do not take an extra dose to make up for a dose thats missed. If too much Nevolat is taken, you should talk to a Dr or go to hospital. Double dosing could increase the risk of side effects, such as nausea, vomiting or low blood sugar.

Like all medicines, Nevolat can cause side effects. The most common are nausea, constipation, tiredness, or a mild stomach upset.

Nausea can be managed by eating smaller, more frequent meals, taking regular sips of a cold drink or consuming ginger or peppermint symptoms. Weight loss treatments tend to cause nausea if more calories are consumed than are required or if you consume too many sugary or carb-heavy foods.

More serious side effects of Nevolat include pancreatitis or an allergic reaction.

If whilst on the Nevolat weight loss injections, you experience severe stomach pain which travels along your back, alongside nausea/sickness or a fever, you should stop treatment and seek immediate medical attention - this is a sign of pancreatitis.

Anaphylaxis or a severe allergic reaction is rare. If you experience swelling of the face, tongue or throat, difficulty breathing or a severe rash or dizziness, stop the treatment and seek emergency medical attention.

Whilst nausea is a common side effect, prolonged nausea can lead to dehydration, particularly upon first starting the treatment. for this reason its important to drink plenty of water

Whilst Nevolat can be prescribed safely to most individuals, it may not be appropriate for everyone. Patients with pre-existing medical conditons should be reviewed carefully by a prescriber as there are circumstances where Nevolat is contraindicated and should be avoided.

Nevolat should not be used in individuals with severe kidney or liver disease, as clinical experience in these groups is limited. In cases of mild to moderate kidney disease, treatment may be considered, but maintaining adequate hydration is essential to minimise the risk of complications.

For those with thyroid disease, treatment may be possible but should first be carefully assessed by a healthcare professional. Clinical studies in rodents have shown a risk of thyroid C-cell tumours, including medullary thyroid carcinoma (MTC) and multiple endocrine neoplasia type 2 (MEN2) - a type of thyroid cancer. Although the relevance to humans remains unproven, Nevolat should be avoided in patients with a personal or family history of MTC or MEN2.

Like other weight loss medications, Nevolat has been associated with cases of acute pancreatitis - a medical emergency. Patients with a history of pancreatitis should be treated with caution, and therapy should be discontinued immediately if pancreatitis is suspected.

As rapid or significant weight loss can increase the risk of gallstone formation, patients who develop upper stomach pain with severe nausea suggestive of gallstones whilst on Nevolat treatment should stop and seek medical advice.

Nevolat is contraindicated in patients who are pregnant, as it may harm an unborn baby. It is also not recommended while breastfeeding, as it is unknown whether the medication is excreted in breast milk.

There is no clinical experience in patients with heart failure and therefore Nevolat is nor recommended for use in these patients.

At Quick Meds, your safety is our top priority, and we operate under strict regulatory standards.

• Every new patient completes a telephone consultation to discuss their starting weight, weight loss journey, and receive personalised diet and exercise guidance to help maximise treatment outcomes safely.

• All orders are clinically reviewed by a qualified prescriber before approval.

• Prescriptions are dispensed and packed under pharmacy supervision, with full data protection compliance.

• All medicines are sourced directly from the manufacturer, in line with MHRA regulations.

Purchasing from unregulated websites can be unsafe, as medicines may be counterfeit or unlicensed. Warning signs include:

• No UK address, registration number, or named pharmacist

• No consultation or health assessment required

• Unrealistic prices or offers for bulk purchases without review

Always ensure an online pharmacy displays the GPhC pharmacy logo, which links to their official registration details.

Before first use, Nevolat pens should be kept in the refrigerator, between 2°C–8°C. Do not freeze the pens and discard if they have been frozen. It is recommended to store in the original carton to protect from light.

After first use, the pen can be kept in the fridge or at room temperature as long as the temperature does not exceed 30°C. Always replace the cap after each use to protect from light. The pens have an in use shelf life of 30 days, after which, any remaining solution must be discarded.

When travelling, keep pens in a cool, insulated pouch away from direct sunlight and heat. Carry the medication with needles in your hand luggage and not in your checked bag. Temperatures in the baggage hold of aicraft may drop below freezing, affecting the medication.

Carry a copy of your prescription or treatment letter for ease through airport security and we would always encourage patients to check with their travel agent for any additional requirements, either during travel or at your destination.